My ma taught me to pack with tissue paper between all your pieces of clothing. You need to fill your case with clothing, not with paperThe new upright wheeling bags has its own limitations on packing.
I mostly start with underclothes on the bottom against the "bars" which are essentially the pull up handle beneath the lining. This evens out the base of the argument for the following layer of clothing. I have everything on a thin wire hanger that comes from the dry cleaners.
These are the lightest weight hangers and will take up the smallest amount of room in the case. The shirt goes on the hanger first, followed by the slacks beneath and the jacket on top. If there is a pin that matches the suit, pin it to the lapel. Then I put three hangers in the case with the hanger beginning at the short end.
And then 3 more hangers beginning at the opposite end. I continue packing like that till all of my clothing on hangers is in the case.
Then I tidily fold one layer over from one end, and then the following layer over from the other end. The hangers stay at opposing end with the clothing folded into the middle. If done correctly your clothing will have just one soft crease where it's been folded. Then I add pajamas rolled up to fit round the fringe or in any empty spaces. Then I place my shoes in shoe mittens or shoe covers and place them round the fringe. Remember not to bring too many pairs of shoes because of the weight limit imposed on baggage by the airlines. I also try to bring one neutral coloured scarf or sweater that may match the majority of the clothing I have packed and I chuck in a tiny travel umbrella. When I empty everything is prepared to hang and barely does anything need ironing. As anyone that has traveled knows, there are never enough hangers in any hotel room. I also carry a cartable steamer, in case there's some wrinkling. The new steamers are little, use tap water from any country, and are twin voltage, so they can be used almost anywhere. I never pack spray bottles or cans in my bags. I wish to put anything that may damage my clothing in my carryon bag.
A plastic closure bag or water-resistant bag helps, but damage has been known to happen, so I play it conservatively by putting that kind of item in my carryon bag. Most hotels today have hair dryers, but if you are used to a stronger dryer, you may want to bring a travel model with you. If coffee is critical first thing in the morning or evening, try the little travel models. Perfect packing takes time and experience - you will soon discover what items you can do without and the ones that make your trip most pleasing.

